Synthesizing chromosomes offers DNA breakthrough
نویسندگان
چکیده
منابع مشابه
Tangled DNA tightens chromosomes
Tangled DNA tightens chromosomes C ramming your vacation wardrobe into your luggage is a breeze compared with the packing job cells perform. Before they can divide, they have to scrunch long DNA molecules into tiny chromosomes. The tangles that form in DNA molecules help this chromosome compression, Kawamura et al. report. The team studies newt chromosomes—they are large and convenient to obser...
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Electron microscopy of HeLa metaphase nucleoids (i.e. whole metaphase cells exposed to 2 M salt and non-ionic detergent) spread by the Kleinschmidt technique, reveals a variety of protein-depleted structures (spreads) derived from chromosomes. Spreads vary in size and shape. At one extreme are oval structures with one or more cores surrounded by a network of supercoiled fibres. These fibres are...
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Mammalian genomes encode about 16 distinct DNA polymerases that participate in different aspects of DNA replication, DNA repair, recombination, or bypass of DNA damage (1, 2). The DNA polymerases used for normal replication generally cannot proceed on damaged DNA. When a damaged site is encountered, replication is stalled at least temporarily, and the lesion may be bypassed by invoking a proces...
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BACKGROUND Newspaper stories can impact behaviours, particularly in relation to research participation. It is therefore important to understand the narratives presented and ways in which these are received. Some work to date assumes journalism transmits existing medical knowledge to a passive audience. This study aimed to explore how newspaper articles present stories about medical research and...
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sciencemag.org SCIENCE Paleoindian, and fishtail points previously provided a roadmap that archaeologists used to trace the spread of Paleoindians throughout the Americas. Such a roadmap is lacking for pre-Clovis sites. Assemblages with distinctive stemmed (“tanged”) chipped-stone projectile points, crescents (lunate-shaped), and leaf-shaped bifaces found in Japan, northeast Asia, western North...
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ژورنال
عنوان ژورنال: Materials Today
سال: 2011
ISSN: 1369-7021
DOI: 10.1016/s1369-7021(11)70271-1